Saturday, March 5, 2016

Insight Into Mesothelioma Cure

               The doctors and researchers are looking for answers related to Mesothelioma cure but have not found any. Before we discuss about mesothelioma cure, it is necessary to know about what is mesothelioma and what are its possible causes. Mesothelioma is a rare cancer of the lining of the lungs and abdomen. High Asbestos exposure is the only known cause of mesothelioma cancers. Asbestos is a natural fibrous mineral that was widely used in the construction process, building material and many manufacturing units. Asbestos breaks into minute particles that float into the air, can be easily inhaled and settle on the clothes of workmen, leaving them and their family members prone to many health hazards.

Understanding Its Symptoms – A Step towards Mesothelioma Cure:

An understanding of mesothelioma symptoms can help in the process of mesothelioma cure. Some common symptoms of mesothelioma are difficulty in breathing, chest pain, and chronic cough. However, many times this disease lies in asymptomatic in the body, which makes mesothelioma cure an impossible task. Once detected, the chances of survival of an average mesothelioma patient are very bleak.

The options for Mesothelioma cure depend upon the different stages of the disease. In the first stage the treatments options depends on factors such as patient’s age, general health, organ affected and the size of tumor. Surgery is used for mesothelioma treatment and cure in the first stage. The doctors remove the tumor and the nearby tissues with a surgical process. However, the doctors use a combination of surgery, radiation therapy and chemotherapy if the tumor has witnessed enormous growth.

Fluid collection in the chest and abdomen takes place in the advance stages of mesothelioma. Mesothelioma cure in these stages involves draining of the fluid to reduce discomfort. This process of treatment is known as Thorancentesis or Paracentesis. After this, the doctors use Surgery followed by radiation and chemotherapy. Treatment and efforts for mesothelioma cure can suffer a severe jolt if the disease strikes back. In that case, the treatment depends on the location of recurrence, and the patient’s medical history.

What If the Efforts For Mesothelioma Cure Fail?

As we have discussed the survival chances of mesothelioma patients are bleak and the possibility of mesothelioma cure are rare. In that case it is necessary to make the patients aware that they are legally entitled to claim compensation for the medical expenses, loss of income, lost earning capacity, pain and the mental trauma they are undergoing. Though the award of compensation cannot bring about mesothelioma cure or compensate for the loss of life, yet it can provide some relief to the mesothelioma victims and their family members.


Mesothelioma Information FAQ

      Pericardial mesothelioma is a serious heart condition which consists of cancerous cells building up on the lining of the heart.  Similarly to pleural and peritoneal mesothelioma, this is a terminal illness due to the importance of the area on which it grows.

What causes pericardial mesothelioma and who are most at risk?

The primary cause of pericardial mesothelioma is exposure to asbestos dust and fibres.  Therefore those at risk are those who are most likely to have inhaled these deadly fibres such as construction workers and asbestos manufacturers.  Those in contact with these people also have a chance of getting pericardial mesothelioma because these people may have asbestos fibres stuck to their clothes or hair.

What are the symptoms of pericardial mesothelioma?

The symptoms of pericardial mesothelioma change from patient to patient.  Usual symptoms include persistent coughing, coughing up blood, shortness of breath, chest pain and palpitations.  Other symptoms patients may experience are nausea, weight loss, vomiting and loss of appetite.

What are the treatments available for pericardial mesothelioma?

There are various different treatments for pericardial mesothelioma although none of these have a high success rate.  Chemotherapy, radiation therapy, dual therapy and surgery are the treatment methods available.  Chemotherapy includes using drugs to kill off cancerous cells and radiation therapy uses doses of radiation to kill cancer cells although this is difficult in the case of pericardial mesothelioma due to the surrounding vital organs such as the heart and lungs.  Dual therapy is a treatment combining radiation therapy with chemotherapy. Surgery comes in two forms; aggressive surgery and palliative procedures.  Aggressive surgery is a very difficult procedure and consists of removing large chunks of cancerous cells in an attempt to gain long term control over the cancer.  Palliative procedures just attempts to lessen the symptoms for the patient.

How much exposure to asbestos is needed for there to be a possibility of getting pericardial mesothelioma?

This depends on how strong and resistant the person is to disease and on the concentration of asbestos in the environment around him.  It is possible to get pericardial mesothelioma from as little as a couple of months of exposure to asbestos although on average it would take a couple of years for enough asbestos fibres to build up to cause cancer.

What is the prognosis for pericardial mesothelioma?

This is highly dependent on how early and how aggressively the cancer is treated.  If pericardial mesothelioma is treated when it has fully developed and matured then the chances of a patient’s survival is very small.  The prognosis could be only a couple of months.

Is there any promising research into cures for pericardial mesothelioma?

Research into cures of pericardial mesothelioma and all other forms of mesothelioma is being done in numerous research labs all over the USA.  Many pharmaceutical companies are also working hard to research new drugs for chemotherapy.  So far, research has been mostly unsuccessful.


10 Options in Treating Mesothelioma

     As with any cancer, treatment for Mesothelioma depends on the location of the cancer, the progression of the disease, the age as well as state of health of the patient.

It is the oncologist who specializes in the disease who will decide on the line of treatment. The disease is difficult to treat and in most cases the prognosis is poor. Treatment options include:

1.    If the diagnosis is done in the early stages surgery may be recommended to remove all cancerous tissues. This means thoracoscopy, VATS or video assisted thoracic surgery, mediastinoscopy (used for staging), or laproscopy.  Often, doctors will advise palliative procedures like chest tube drainage and pleurodesis, thoracoscopy and pleurodesis, pleuroperitonial shunt, or pleurectomy, which treat the symptoms of mesothelioma rather than the disease.

2.    Radiation is prescribed aggressively for mesothelioma patients and is often given in combination with surgery or in order to control symptoms, palliatively. Research on using radiation therapy using implants or UV light therapy is in progress as traditional radiation therapy damages surrounding healthy tissue.

3.    Chemotherapy is an option and around 12-20% of patients respond to the drugs. Anti-cancer drugs destroy cancer cells and prevent their spread. In mesothelioma, chemotherapy is not considered to be curative. The aim is to prevent spread of the disease; shrink the tumor prior to surgery, known as neoadjuvant therapy; to annihilate any remains of the tumor in the body post surgery; and to relieve pain and other discomfort, palliative chemotherapy. Experts recommend prescribing premetrexed along with cisplastin. These drugs have shown positive results and this is now standard care for Mesothelioma not treatable by surgery.

4.    Biological therapy using interleukin 2.

5.    Immunotherapy where the body’s own immune system is stimulated to fight the disease. Biological response modifiers, BRMs, are used in treatment. These enhance the functions of the immune system; regulate metabolic reactions that promote growth of cancers; alter cancer cell division; block or reverse processes that lead to formation of cancers; and prevent spread of cancer.

6.    Gene therapy, where attempts are made to correct the gene sequence that causes the cancer. This is of two kinds, replacement gene therapy and knockout gene therapy. 

7.    Administration of lovastatin, a cholesterol lowering drug.

8.    Photodynamic treatment where a photosensitive medication is activated using a laser. This is done during the surgical removal of cancerous tissues.

9.    Draining of fluid in the chest or abdominal cavity followed by introduction of medications into the cavity to prevent fluid accumulation is done for patients who have uncontrolled fluid accumulation and intense discomfort stemming from it.

10.    Combination therapy or Trimodal therapy which means surgery accompanied by radiation and chemotherapy. 

Often, complementary medicines are also used. Termed to be holistic this kind of treatment focuses on a patient’s physical, mental, emotional, and spiritual well being.

In the case of Mesothelioma which is untreatable one can opt for clinical trials of new treatments that are in progress in several research laboratories and centers. The best advice on the line of treatment would be that recommended by the oncologist or physician.